Bruce Rittmann,Rosa Krajmalnik-Brown,Husen Zhang,John Dibaise,Michael Crowell
申请号：
US13579326
公开号：
US20130230498A1
申请日:
2011.02.16
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides for microbial compositions and methods for reducing the concentration of short-chain fatty acids in the gut as a way to reduce energy uptake and manage obesity. More specifically, the invention provides for decreasing short-chain fatty acids available for absorption in the human gut, such as acetate, using one or more of: a probiotic including a homo-acetogenic, acetate oxidizing bacterium that converts acetate to H2 a probiotic including an acetoclastic methanogen a microbial electrolysis cell comprising a homo-acetogenic bacterium and/or an acetoclastic methanogen a prebiotic that enhances the growth or function of acetate-scavenging microbiota or a highly selective antibiotic that targets H2-oxidizing methanogens.
