Randall B. Pugh,Jason M. Tokarski,Brett A. Coldren
申请号:
US13890066
公开号:
US20130338611A1
申请日:
2013.05.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention discloses methods and apparatus for providing pulsatile release of active agents via a punctal plug inserted into a punctum. A tube is provided which may be inserted into a cavity of a punctal plug. One or more pulsatile delivery units are arranged in a generally linear fashion within the tube. The pulsatile delivery units include a core comprising the active agent and an encapsulation layer around the core.