Connolly Stephen,Ebden Mark Richard,Langer Thomas,Steven Alan Robert,Stewart Craig Robert,Tomlin Paula Margaret,Walters Iain Alastair Stewart,Williams Andrew John
申请号:
NZ71917612
公开号:
NZ719176A
申请日:
2012.07.10
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed herein is the pyrimidine sulphonamide compound of formula (I) N-(6-((2R,3S)-3,4-dihydroxybutan-2-yloxy)-2-(4-fluorobenzylthio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide or a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. The compound is intended of use in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial. Intermediates used in the manufacture of the compound include the compounds of formula (VI), (XI) and (XII).