The present invention provides pyrazole derivatives,e.g., a compound of Formula (I), and their uses in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.本發明提供例如式(I)化合物之吡唑衍生物,及其在治療惡性疾病及病症之方法中以及用於治療發炎疾病及病症之方法中的用途。