A device isolates a substance from blood. The substance includes particles with an effective diameter that is within a range defined by effective diameters of constituents of blood. The device comprises a first sheet of graphene including a first plurality of apertures. The first plurality of apertures are configured to pass objects with an effective diameter less than or equal to the effective diameter of the particles of the substance. The device comprises a second sheet of graphene including a second plurality of apertures. The second plurality of apertures are configured to pass objects with an effective diameter less than the effective diameter of the particles of the substance. The device may be configured to include a conduit system. The device may be configured to operate according to a reversible cycle.本發明係有關於一用於自血液單離物質之裝置。該物質包括其有效直徑係在一藉血液之成份的有效直徑而界定之範圍內的顆粒。該裝置包含第一片包括第一複數之細孔的石墨烯。該第一複數之細孔被建構為通過其有效直徑小於或等於該物質之顆粒的有效直徑之物件。該裝置包含第二片包括第二複數之細孔的石墨烯。該第二複數之細孔被建構為通過其有效直徑小於該物質之顆粒的有效直徑之物件。該裝置可被建構包括一導管系統。該裝置可被建構為根據一可逆循環而進行操作。