HERSHFIELD MICHAEL DURHAM,KELLY SUSAN J. CHAPEL HILL
申请号:
HU0103205
公开号:
HU229774B1
申请日:
1999.08.05
申请国别(地区):
HU
年份:
2014
代理人:
摘要:
The present invention relates, in general, to urate oxidase (uricase) proteins and nucleic acid molecules encoding same. In particular, the invention relates to uricase proteins which are particularly useful as, for example, intermediates for making improved modified uricase proteins with reduced immunogenicity and increased bioavailability.