The present invention relates to the novel epidemic diarrhea virus (PEDV) of pig and the isolation of manufactured vaccine composition therefrom. Vaccine composition protects pig from PED sickness influences, is protective from various strain crosses, no matter variant or prototype, All Around The World previous cycle. Vaccine is provided by it all kill and live virus form, as from strain Calaf14, it is proposed that specific amino acid is modified, and the coded sequence that other all PEDV of their performance as vaccine are strained can be improved.
