IMIDAZOLE DERIVATIVES AS MGLUR5 ANTAGONISTS

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专利权人:

F HOFFMANN-LA ROCHE AG

发明人:

JAESCHKE GEORG,VIEIRA ERIC,LINDEMANN LOTHAR,WICHMANN JUERGEN

申请号：

ZA201109451

公开号：

ZA201109451B

申请日:

2011.12.21

申请国别(地区):

ZA

年份:

2012

代理人:

摘要：

The present invention relates to imidazole derivatives of the general formula wherein R1, R2, R3, and R4 are as defined in the specification and to pharmaceutically acceptable salts thereof. Compounds of formula I are metabotropic glutamate receptor antagonists. They can be used in the treatment or prevention of mGluR5 receptor mediated disorders.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/