An electrosurgical unit having micro/nano structure formed thereon and the manufacturing method thereof are disclosed, in which the electrosurgical unit is formed by the irradiation of a laser beam upon a blade so as to have a hybrid of micro/nano elements formed on the surface of the blade. The application of the hybrid of micro/nano elements on the surface of the blade has proven to be a valuable asset not only in providing a non-stick surface and a good heat dissipation ability to the blade, but also in providing a electrosurgical blade that will not release any toxic material under high temperature.