Liu, Liping,Bot, Adrian,Diamond, David C.,Xie, Zhidong
申请号:
AU2005265182
公开号:
AU2005265182B2
申请日:
2005.06.17
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed.