WANG, LI-YING N-1401 HUI YUAN SERVICE APARTMENT,BAO, MU-SHENG N-1401 HUI YUAN SERVICE APARTMENT,YU, YONG-LI N-1401 HUI YUAN SERVICE APARTMENT
申请号:
DK06705636
公开号:
DK1883647T3
申请日:
2006.02.13
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The invention provides nine oligonucleotides with sequences of SEQ ID NO: 1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonucleotides or their functional homologues or the composition comprising the oligonucleotides. The oligonucleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B cell neoplastic cells.