FUNDAÇÃO BUTANTAN;BIOTICK PESQUISA E DESENVOLVIMENTO TECNOLÓGICO LTDA.
发明人:
Ana Marisa Chudzinski-Tavassi,Bárbara Athayde Vaz Galvão da Silva,Kerly Fernanda Mesquita Pasqualoto,Leo Kei Iwai,Rafael Marques Porto
申请号：
US16485035
公开号：
US20200095289A1
申请日:
2018.02.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to novel hybrid peptides developed from the combination of membrane surface protein peptide fragments present in anaplasmosis microorganisms, and in particular, bacteria of the species Anaplasma marginale. The present invention further relates to hybrid peptide sets, compositions and kits comprising such novel hybrid peptides, their uses and methods of inducing immune response. Each hybrid peptide, according to the present invention, comprises two or more peptide fragments of amino acid sequences as defined in the present invention linked together by means of a spacer element. The combined peptide fragments are protein peptide fragments of MSP1, MSP1a, MSP1b, MSP2, MSP2-HRV, MSP3, OMP7, OMP8, VirB9 and VirB10.
