Dinesh S. RAO,Ella WATERS,Norma I. RODRIGUEZ-MALAVE,Thilini FERNANDO
申请号:
US14776458
公开号:
US20160145692A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The instant disclosure relates to the finding that lincRNA expression is associated with particular cytogenetic abnormalities and is related to disease pathogenesis of certain cancers. Long intergenic non-coding RNAs (lincRNAs) have been found to play a role in gene regulation, but their expression has not been described in B acute lymphoblastic leukemia (B-ALL). Methods and compositions are provided regarding B-ALL associated long intergenic RNAs (BALIRs).