LEE, HO,YOUL - JI, SEUNGHEE,YOO, JAE HO,BYUN, JOONSEOK,KIM, SEUNGIN,KO, DONG HYUN,JUNG, WON,HYUK - LEE, JU HYUN,RYU, SHIN,YOUNG - BAK, HYOUNG ROK,PARK, CHI HYE,KIM, DONG HYUN,JUNG, JIN WOO,LEE, KEUNHO
申请号：
ARP180102041
公开号：
AR112283A1
申请日:
2018.07.20
申请国别(地区):
AR
年份:
2019
代理人:
摘要：
1. Characteristic 1: pharmaceutical ingredients for the prevention or treatment of non-alcoholic fatty liver disease or degreasing, including compounds represented by formula (1) below or acceptable salts for pharmaceutical use as active ingredients, R1 is hydroxyl, carboxi, O hydroxysulfonylhydrazide (c8332183318324a1)；R2 and R3 are independent hydrogen, tar c8332183318324；Hydroxi (c83218c83318324 matrix)；1. Carbamoil (lease No. c8321833124j)；Carboxi, carboxi (rent c832131)(straight c83325583； 83220) (lease c833213183248a) or (lease c833283218383218321) (lease c8332131833183318324248a)Or rim and rim1. Form c8332383318327c together with their carbon atoms；R830808 is hydrogen or carboxi (c83218c833124248a)；R83099a is amino of hydrogen, halogen (tar c831832424248a), uncle (tar c83183242e), O di (tar c831216c8383324a), and r8310y r8311son is independent tar c833218331832626；R831222 and r8313 are hydrogen, hydrogen Xi and alcoxi c8332183318324, respectively；1. Lease of c83218331 and 83242431；A. halogen, nitrogen, cyanogen, amino acid (grass c833121) c8324248a) amine, di (tar c83218c8332424248a) amine, acetamide, methyl rice, alkane c83216c83183242424248a；Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Ya Ya Ya Ya Ya Ya Ya Ya Ya Ya Ya Ya Ya Ya Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi Xi；N is an integer from 0 to 3.Reivindicación 1: Una composición farmacéutica para prevenir o tratar enfermedad del hígado graso no alcohólico (NAFLD) o dislipidemia que comprende un compuesto representado por la fórmula (1) a continuación o una sal aceptable para uso farmacéutico del mismo como principio activo, en donde R¹ es hidroxi, carboxi, o hidroxisulfonil(alquilo C₁₋₄)； R²
