SHIMADA, KOUSEI,ONISHI, YOSHIYUKI,MORI, MAKOTO,TOKUMARU, ERI
申请号:
MYPI 20094121
公开号:
MY148434A
申请日:
2008.04.02
申请国别(地区):
MY
年份:
2013
代理人:
摘要:
THE PRESENT INVENTION RELATES TO A NOVEL FUSED BICYCLIC HETEROARYL DERIVATIVE OR A PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, WHICH HAS AN EXCELLENT HYPOGLYCEMIC EFFECT OR TREATS AND/OR PREVENTS THE ONSET OF A DISORDER OF CARBOHYDRATE OR LIPID METABOLISM OR A DISEASE MEDIATED BY PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) γ. SOLUTION A COMPOUND HAVING THE GENERAL FORMULA (I): [FORMULA 1] WHEREIN R1 REPRESENTS A C1-C6 ALKYL GROUP, A C6-C10 ARYL GROUP WHICH MAY BE SUBSTITUTED WITH 1 TO 5 GROUP(S) INDEPENDENTLY SELECTED FROM SUBSTITUENT GROUP A, OR THE LIKE; R2 REPRESENTS A C1-C6 ALKYL GROUP; R3 REPRESENTS A C6-C10 ARYL GROUP WHICH MAY BE SUBSTITUTED WITH 1 TO 5 GROUP(S) INDEPENDENTLY SELECTED FROM SUBSTITUENT GROUP A, OR THE LIKE; Q REPRESENTS A GROUP REPRESENTED BY THE FORMULA =CH-OR A NITROGEN ATOM; AND SUBSTITUENT GROUP A REPRESENTS A HALOGEN ATOM, A C1-C6 ALKYL GROUP, A C1-C6 HYDROXYALKYL GROUP, AND THE LIKE, OR A PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF.