Frank Osterkamp,Heiko Hawlisch,Gerd Hummel,Tobias Knaute,Ulf Reimer,Ulrich Reineke,Bernadett Simon,Uwe Richter,Edgar Specker,Markus Woischnik,Mark R. Hellberg
申请号：
US13916019
公开号：
US09458198B1
申请日:
2013.06.12
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed are cyclic, peptide-based novel compounds having NPR-B agonistic activity. Preferred compounds are cyclic peptides containing conventional or non-conventional L- or D-amino acid residues connected to one another via peptide bonds. In some embodiments, provided herein are a cyclic peptide compound with a ring size that is significantly reduced as compared to known NPR-B agonists, such as CNP.
