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PRODUCTION AND USE OF NOVEL PEPTIDE-BASED AGENTS FOR USE WITH BI-SPECIFIC ANTIBODIES
专利权人:
发明人:
申请号:
EP02725464.8
公开号:
EP1372718B1
申请日:
2002.04.03
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present disclosure relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic linker is conjugated to one or more therapeutic or diagnostic agents or enzymes. The disclosure provides constructs and methods for producing the bi-specific antibodies or antibody fragments, as well as methods for using them.
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