A therapeutic treatment system (1) includes a holding section (13) configured to hold a biological tissue, electrodes (23a, 23b) provided in the holding section (13) and capable of outputting first high-frequency energy for sealing the biological tissue at a first sealing temperature and second high-frequency energy for dissecting the biological tissue at a first dissection temperature, electrodes (24a, 24b) provided in the holding section (13) and capable of outputting first thermal energy for sealing the biological tissue at a second sealing temperature higher than the first sealing temperature and second thermal energy for dissecting the biological tissue at a second dissection temperature lower than the first dissection temperature, and a control section (31) configured to control temperature of each of the electrodes (23 a, 23b, 24a, 24b) to output the second thermal energy after the output of the first high-frequency energy.