PROBLEM TO BE SOLVED: To provide a prefilled syringe having both of medicament non-adsorbability and heat resistance capable of withstanding a 121°C sterilization test at a low cost, while retaining transparency, formability, and shock resistance of a barrel to be filled with a medicament.SOLUTION: A barrel 2 constituting a prefilled syringe 1 includes a multilayer structure in which an innermost layer composed of a cyclic polyolefin resin and an outer layer composed of a polypropylene resin are aligned via an adhesion layer composed of a polyolefin-based adhesive resin. This configuration can provide a low-cost prefilled syringe 1 having both of the medicament non-adsorbability and the heat resistance, while retaining the transparency, formability, and shock resistance.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT【課題】薬剤が充填されるバレルの透明性、成形性及び耐衝撃性を維持しつつ、薬剤非吸着性と、121℃滅菌試験に耐えうる耐熱性を兼ね備えたプレフィルドシリンジを低コストで提供すること。【解決手段】本発明は、プレフィルドシリンジ1を構成するバレル2が、環状ポリオレフィン樹脂からなる最内層と、ポリプロピレン樹脂からなる外層が、ポリオレフィン系接着性樹脂からなる接着層を介して並んでいる多層構造、を含んでなるので、透明性、成形性及び耐衝撃性を維持しつつ、薬剤非吸着性及び耐熱性を兼ね備えた低コストのプレフィルドシリンジ1となる。【選択図】図1
