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ANTIGEN-BINDING PROTEINS
专利权人:
Laurent Jespers;Michael Steward;Thil Dinuk Batuwangala
发明人:
Thil Dinuk Batuwangala,Laurent Jespers,Michael Steward
申请号:
US13322229
公开号:
US20120064064A1
申请日:
2010.05.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to antigen binding proteins comprising an immunoglobulin heavy chain and an immunoglobulin light chain, wherein the heavy chain comprises an epitope binding domain linked to the n-terminus of CH1-CH2-CH3, and the light chain comprises an epitope binding domain linked to the n-terminus of CL, wherein one or more epitope-binding domains are linked to the C-terminus of the immunoglobulin heavy chain, and/or one or more epitope-binding domains are linked to the C-terminus of the immunoglobulin light chain, methods for making such proteins, and uses thereof.
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