Joung Han Yim,Il Chan Kim,Doc Kyu Kim,Se Jong Han,Hyoung Seok Lee,Bhattarai Hari Datta,Jung Eun Kim,Tai Kyoung Kim,Hyun Cheol Oh,Dong-Gyu Jo,Cheolsoon Lee,Keun-Sik Kim,Pyung Cheon Lee,Mi Ra Park,Yu-Ky
申请号:
US13900361
公开号:
US08703814B1
申请日:
2013.05.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to pharmaceutical and food compositions for preventing or treating diabetes or obesity, and more particularly to pharmaceutical compositions and functional foods for preventing or treating diabetes or obesity, which contain, as an active ingredient, a novel compound synthesized from a compound separated from an extract of the Stereocaulon alpinum. The novel compounds of the invention have very excellent PTP-1b (protein tyrosine phosphatase-1b) inhibitory activities, act selectively only on PTP-1b among protein tyrosine phosphatases, and are substantial PTP-1b inhibitors which are effective in preventing or treating diabetes or obesity.