ST. JUDE CHILDREN'S RESEARCH HOSPITAL;MMV MEDICINES FOR MALARIA VENTURE;RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
发明人:
GUY, RODNEY KIPLIN,ZHU, FANGYI,GUIGUEMDE, WENDYAM ARMAND,FLOYD, DAVID,KNAPP, SPENCER,STEIN, PHILIP,CASTRO, STEVE
申请号:
CA2846507
公开号:
CA2846507A1
申请日:
2012.08.24
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl-,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.