The University of Queensland;The Provost, Fellows Foundation Scholars and the other Members of Board of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
发明人:
O'Neill, Luke,Coll, Rebecca,Cooper, Matt,Robertson, Avril,Schroder, Kate,ONeill, Luke
申请号:
AU2016222278
公开号:
AU2016222278A1
申请日:
2016.02.16
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
ABSTRACT The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.