CHOUNG, SE YOUNGKR,정세영,KIM, DONG JOONKR,김동준,YANG, SEUNG WONKR,양승원,CHOI, SANG HOKR,최상호,KANG, DO HYUNGKR,강도형,HEO, SOO JINKR,허수진
申请号：
KR1020140071960
公开号：
KR1020150143912A
申请日:
2014.06.13
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a pharmaceutical composition for preventing and treating retinal diseases, comprising a Spirulina maxima extract. The Spirulina maxima extract of the present invention and allophycocyanin (APC), R-phycoerythrin (R-PE), and C-phycocyanin (C-PC), which are components of the Spirulina maxima extract show an inhibiting effect of pyridinium bis-retinoid (A2E) oxidized by blue light and apoptosis, and thus can be helpfully used as active ingredients of the composition for preventing and treating retinal diseases.COPYRIGHT KIPO 2016본 발명의 스피루리나(Spirulinamaxima) 추출물 및 이의 성분인 알로피코시아닌(Allophycocyanin, APC), 알-피코에리스린(R-phycoerythrin, R-PE), 씨-피코시아닌(C-phycocyanin, C-PC)은 청색광에 의해 산화된 A2E(pyridinium bis-retinoid) 및 세포사멸을 억제하는 효과를 나타내므로, 망막질환 예방 및 치료용 조성물의 유효성분으로서 유용하게 사용될 수 있다.
