SINGAPORE HEALTH SERVICES PTE LTD;60O PHARMACEUTICALS LLC;NATIONAL UNIVERSITY OF SINGAPORE
发明人:
VASUDEVAN, SUBHASH,SUNG, CYNTHIA,RATHORE, ABHAY,WATANABE, SATORU,LOW, JENNY,OOI, ENG EONG,DOW, GEOFFREY S.,MORRISH, GLYNN,REID, MARK
申请号:
PH12015502128
公开号:
PH12015502128A1
申请日:
2015.09.15
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
Methods of treating a dengue virus (DENV) infection in a human subject, comprising administering to the human subject a compound of Formula (I), or pharmaceutical composition comprising a compound of Formula (I):A compound of Formula (I) can be administered within onset of fever to 72 hours of fever onset due to dengue infection and then every 6 to12 hours until there is an improvement in the infection or between from about 1 day to about 10 days. The methods of the invention can be used to treat primary and secondary DENV1-4 viral infections.