Sara Post Hansen,Rene Faber,Udo Reichl,Michael Wolff,Anders Peter Gram
申请号:
US13906541
公开号:
US09109201B2
申请日:
2013.05.31
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to methods for purification of Vaccinia viruses (VV) and/or Vaccinia virus (VV) particles, which can lead to highly pure and stable virus preparations of predominantly biologically active viruses. The invention encompasses purifying a virus preparation in a sterilized way with high efficiency and desirable yield in terms of purity, biological activity and stability, aspects advantageous for industrial production.