LESUISSE, DOMINIQUE,DUTRUC-ROSSET, GILLES,HALLEY, FRANCK,BABIN, DIDIER,ROONEY, THOMAS
申请号：
CA2497351
公开号：
CA2497351C
申请日:
2003.09.03
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to the new derivatives of general formula (I) in which R3 is a (1-6C) alkyl, aryl, aryl (1-6C) alkyl, heteroaryl, heteroaryl (1-6C) alkyl, aryl or heteroaryl radical. ô a cycloalkyle (1-10C), heterocycle, heterocycloalkyle, cycloalkyle, adamantyle, polycycloalkyles, alényle, alkynyle, CONR1R2, COOR1, SO2R1, C =； NH) R1, C =； NH) NR1； R5, R6 are independently of one another chosen from the radicals according to halogen, CN, NO2, NH2, OH, COOH, C (O) OR8, -OC (O) R8, NR8R9, NHC (O) R8, C (O) NR8R9, NHC (S) R8, C (S) NR8R9, SR8, S (O) R8, SO2R8, NHSO2R8, SO2NR8R9, -O-SO2R8, -SO2-O-R8, trifluoromethyl, trifluoromethoxy, (1 -6C) alkyl, (1-6C) alkoxy, aryl, aryl (1-6C) alkyl, heteroaryl, heteroaryl (1-6C) alkyl, heterocycle, cycloalkyl, alkenyl, alkynyl, adamantyl, polycycloalkyls.La présente invention concerne les nouveaux dérivés de formule générale (I)dans laquelle R3 est un radical (1-6C)alkyle, aryle, aryle(1-6C)alkyle,hétéroaryle, hétéroaryle(1-6C)alkyle, aryle ou hétéroaryle fusionné ô uncycloalkyle (1-10C), hétérocycle, hétérocycloalkyle, cycloalkyle, adamantyle,polycycloalkyles, alkényle, alkynyle, CONR1R2, COOR1, SO2R1, C=；NH)R1,C=；NH)NR1； R5, R6 sont indépendamment l'un de l'autre choisis parmi lesradicaux suivant halogène, CN, NO2, NH2, OH, COOH, C(O)OR8, -O-C(O)R8, NR8R9,NHC(O)R8, C(O)NR8R9, NHC(S)R8, C(S)NR8R9, SR8, S(O)R8, SO2R8, NHSO2R8,SO2NR8R9, -O-SO2R8, -SO2-O-R8, trifluorométhyle, trifluorométhoxy, (1-6C)alkyle, (1-6C)alcoxy, aryle, aryle(1-6C)alkyle, hétéroaryle, hétéroaryle(1-6C)alkyle, hétérocycle, cycloalkyle, alkényle, alkynyle , adamantyle,polycycloalkyles.
