The present invention provides a pharmaceutical combination for treatment of brain tumors in a subject in need thereof, comprising a dendritic cell vaccine containing dendritic cells pulsed with an irradiated antigen, and an antibody targeting immune checkpoint proteins of T cells. The present invention also provides an use of a dendritic cell vaccine and an antibody which targets immune checkpoint proteins on T cells in the preparation of a pharmaceutical combination for treatment of brain tumors.本發明提供一種併用藥物組合，其係包括樹突細胞疫苗以及抗T細胞免疫檢查點蛋白抗體，藉由前述藥物之組合施用，可有效利用於腦腫瘤病患之治療，其中該樹突細胞疫苗包括經放射線處理之抗原所刺激之樹突細胞。本發明亦提供一種利用樹突細胞疫苗與抗T細胞免疫檢查點蛋白抗體於製備治療腦腫瘤併用藥物之用途，其中該樹突細胞疫苗包括經放射線處理之抗原所刺激之樹突細胞。
