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Stable formulations of a hyaluronan-degrading enzyme
专利权人:
HALOZYME INC.
发明人:
VAUGHN DANIEL EDWARD,YANG TZUNG-HORNG,LABARRE MICHAEL JAMES,CASTER CHRISTOPHER L.,NICOL FRANCOIS,KIM DONGHYUN
申请号:
NZ61833112
公开号:
NZ618331A
申请日:
2012.06.15
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Discloses a stable co-formulation composition, wherein: the composition has a pH of between or between about 6.8 and 7.8; and the composition comprises: a) an insulin or insulin analogue; b) a hyaluronidase; c) NaCl; d) a stabilising agent or agents; and e) one or more preservative agents comprising a phenolic preservative, whereby the composition is stable for at least 6 months at a temperature from or from about 2°C to 8°C, inclusive, and/or for at least 14 days at a temperature from or from about 20°C to 30°C, inclusive.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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