There is provided a sole stimulation sock, in which an inner side of a sole portion between a heel portion and a toe portion is formed with projected portions and recessed portions, in which a proportion of an area of the projected portions, with respect to the sum of the areas of the projected portions and the recessed portions, is 26% to 68%, in which the difference between a proportion of an area of the projected portions in any one division region of four division regions of the inner side of the sole portion and a proportion of an area of the projected portions in other division regions is less than or equal to 30%, in which the average value of the areas of the projected portions is 7 mm2 to 650 mm2, and in which the recessed portions are knitted by mesh knitting.