PROBLEM TO BE SOLVED: To provide a patch which has high skin permeability of an antiinflammatory analgesic, has no stickiness after removal, and is hard to peel/turn up.SOLUTION: The patch is formed of a water-containing cataplasm containing (A) a hardly water-soluble nonsteroid antiinflammatory analgesic, (B) N-methyl-2-pyrrolidone, (C) a smectite-based clay mineral, (D) a nonionic surface active agent, (E) 5-25 mass% glycerol, (F) polyacrylic acid, a salt thereof or a partially neutralized product thereof, and (G) a polyvalent metal salt and having a water content of 55-80 mass%, laminated on a support.COPYRIGHT: (C)2011,JPO&INPIT【課題】消炎鎮痛剤の皮膚透過性が高く、剥離後のべたつきがなく、かつ貼り付けた後にはがれ・めくれが少ない貼付剤を提供する。【解決手段】(A)水難溶性非ステロイド系消炎鎮痛剤と、(B)N-メチル-2-ピロリドンと、(C)スメクタイト系粘土鉱物と、(D)非イオン性界面活性剤と、(E)グリセリン5~25質量%と、(F)ポリアクリル酸、その塩又はその部分中和物と、(G)多価金属塩とを含有し、含水率が55~80質量%である含水性膏体が、支持体に積層されてなる貼付剤。【選択図】なし
