MARSHALL, COLIN,CLUNAS, SCOTT,STOREY, JOHN MERVYN DAVID,SINCLAIR, JAMES PETER,BADDELEY, THOMAS CRAVEN,ISHAQ, AHTSHAM,SIMPSON, MICHAEL,WILLIAMSON, CRAIG,WOOD, BARRY ALAN,WISCHIK, CLAUDE MICHEL,HARRINGT
申请号：
RSP20160880
公开号：
RS55237B1
申请日:
2011.08.15
申请国别(地区):
RS
年份:
2017
代理人:
摘要：
The invention relates to compounds of general formula (I): wherein: each of R1 and R9 is independently selected from: &mdash；H, C1-4alkyl, C2-4alkenyl, and halogenated C1-4alkyl； each of R3NA and R3NB is independently selected from: &mdash；H, C1-4alkyl, C2-4alkenyl, and halogenated C1-4alkyl； each of R7NA and R7NB is independently selected from: &mdash；H, C1-4alkyl, C2-4alkenyl, and halogenated C1-4alkyl； and wherein: each of RA and RB is independently selected from: C1-4alkyl, halogenated C1-4alkyl, and C6-10aryl； or RA and RB are linked to form a group selected from: C1-6 alkylene and C6-10 arylene； and pharmaceutically acceptable salts thereof, which are useful in the treatment of, for example, Alzheimer's disease. In other aspects the invention also relates to novel formulations of 3,7-diamino-10H-phenothiazinium salts.
