Thuring, Johannes Wilhelmus John f.,Van Roosbroeck, Yves Emiel Maria,Zhuang, Wei,MacDonald, Gregor James,Stanislawski, Pauline Carol,Van Den Keybus, Frans Alfons Maria
申请号：
AU2009226988
公开号：
AU2009226988B2
申请日:
2009.03.18
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to l-aryl-3-aniline-5-alkyl-l, 2,4-triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
