Provided are a PGE 2 production suppressant, an anti-inflammatory agent, a melanin production suppressant and a skin whitening agent, which are further excellent. The present invention relates to an anti-inflammatory agent composition, a PGE 2 production suppressant composition, a melanin production suppressant composition, or a skin whitening agent composition comprising one or more kinds selected from pentaerythritol, an alkyl acetal derivative of pentaerythritol represented by the formula (1) described below, and an alkyl acetal derivative of pentaerythritol represented by the formula (2) described below: wherein R 1 and R 2 may be different from each other to represent C 1-4 alkyl and wherein R 3 to R 6 may be different from each other to represent C 1-4 alkyl.