Disclosed are a method and/or system for determining a suggested change in arecommended therapy for a patientbased, at least in part, on sensor measurements, and generating an alert to anattendant in a hospital environment upon detection ofthe suggested change. In another embodiment, a method and/or system isdirected to automatically determining a maximum intervalto alert an attendant following receipt of a measurement at an operatorinterface. In yet another embodiment, a method and/orsystem is directed to blood-glucose sensor calibration.