Chimeric HIV Env proteins comprising CD4 mini-proteins or CD4 mimetics that are capable of inducing neutralizing antibody responses against cryptic Env epitopes

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专利权人:

Susan W Barnett

发明人:

Susan W Barnett,Indresh K Srivastava

申请号：

US12859356

公开号：

US08226955B2

申请日:

2010.08.19

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Env-CD4 polypeptide complexes and hybrids that expose cryptic epitopes important in virus neutralization are disclosed. Method of diagnosis, treatment and prevention using the polypeptides are also provided.

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