DIODONE, RALPH,LAUPER, STEPHAN,MAIR, HANS-JUERGEN,PUDEWELL, JOHANNES,WIERSCHEM, FRANK
申请号：
SG2012034161
公开号：
SG180786A1
申请日:
2010.11.08
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The present invention is related to an improved method for the manufacture of Micro- precipitated Bulk Powder (MBP) containing the active pharmaceutical ingredient Propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide and Hydroxypropylmethylcellulose Acetate Succinate (HPMCAS). The invention is further directed to pharmaceutical compositions containing said MBP, as well as its use in the manufacture of medicaments for the treatment of cancer. Formula (I).
