Robert B. Dubridge,Bryan D. Lemon,Richard J. Austin,Luke Evnin,Jeanmarie Guenot
申请号:
US15600582
公开号:
US10100106B2
申请日:
2017.05.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are single domain serum albumins binding proteins with improved thermal stability, binding affinities, and robust aggregation profiles. Also described are multispecific binding proteins comprising a single domain serum albumin binding protein according to the instant disclosure. Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of using such formulations are provided.