BARF, TJEERD A.,JANS, CHRISTIAAN GERARDUS JOHANNES MARIA,MAN, DE ADRIANUS PETRUS ANTONIUS,OUBRIE, ARTHUR A.,RAAIJMAKERS, HANS C.A.,REWINKEL, JOHANNES BERNARDUS MARIA,STERRENBURG, JAN-GERARD,WIJKMANS,
申请号:
CA2841886
公开号:
CA2841886C
申请日:
2012.07.11
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
There are provided 6-5 membered fused pyridine ring compounds according toformula l(see formula I)or a pharmaceutically acceptable salt thereof or to pharmaceuticalcompositions comprising thesecompounds and their possible use in therapy. The disclosure relates to the useof 6-5 membered fusedpyridine ring compounds according to formula l for inhibiting Bruton'sTyrosine Kinase (Btk) in vitro whichmay allow the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.