The present invention discloses a pharmaceutical composition containing GLP-1 analogs, including GLP-1 analogs, buffers, stabilizers, isotonic agents and preservatives. The present invention has the advantage of providing a formulation suitable for clinical multiple injections by adding some ingredients which can be accepted by the human body and enhancing the stabilization of the physicochemical and biological activity of the GLP-1 analog. This preparation can effectively prevent the active ingredient GLP-1 analogs from degradation, oxidation, precipitation and other factors leading to lose efficacy or crystallization, so as to facilitate transport, long-term preservation and clinical use.