A graft with adjustable stenosis having a length of tube having tube wall with a central passage between an inlet end and an outlet end. A flexible barrier is located in the length of tube, that, in a default position, forms a narrowed section in the central passage and establishes a stenosis fluid chamber between the tube wall and the flexible barrier. An aspiration port system includes a port reservoir, containing fluid, and a needle entry seal, for needle access to the port reservoir to remove or add fluid. A channel is in fluid communication with the stenosis fluid chamber, the stenosis fluid chamber containing stenosis fluid chamber fluid. A separator is between the channel and the port reservoir. The flexible barrier is biased to a default narrow position. Responsive to fluid being removed from the port reservoir, the flexible barrier moves to increase the diameter of the narrowed section.