FOORD, ORIT,GREEN, LARRY,FENG, XIAO,KLAKAMP, SCOTT,HAAK-FRENDSCHO, MARY,LIANG, MEINA L.,LEE, ROZANNE,FAGGIONI, RAFFAELLA,SENALDI, GIORGIO,MANCHULENKO, KATHY,SU, QIAOJUAN JANE,BABCOOK, JOHN S.,KANG, JA
申请号：
CA2508375
公开号：
CA2508375C
申请日:
2003.12.02
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Antibodies directed to the antigen TNFa and uses of such antibodies. Inparticular, fully human monoclonal antibodies directed to the antigen TNFa.Nucleotide sequences encoding, and amino acid sequences comprising, heavy andlight chain immunoglobulin molecules, particularly sequences corresponding tocontiguous heavy and light chain sequences spanning the framework regionsand/or complementarity determining regions (CDR's), specifically from FR1through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressingsuch immunoglobulin molecules and monoclonal antibodies.
