National Institute of Biological Sciences; Beijing
发明人:
Niu Huang,Yu Zhou,Xingyu LIN
申请号：
US15847907
公开号：
US20180111908A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides novel compounds and compositions comprising a 5-HT2B antagonist of formula I:and related methods for treating a person having a disorder characterized by undesirable 5-HT2B receptor signaling, such as migraine, irritable bowel syndrome (IBS), pulmonary arterial hypertension (PAH), fibrosis, hepatocellular cancer, a small intestinal neuroendocrine tumor, cardiovascular disorders, and gastrointestinal (GI) tract disorders.
