GLAXOSMITHKLINE LLC;WONG, Man, Yi;MONCK, Myrna, A.;ZHANG, Kai
发明人:
MONCK, Myrna, A.,WONG, Man, Yi,ZHANG, Kai
申请号:
USUS2012/032464
公开号:
WO2012/141978A3
申请日:
2012.04.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to a method for reducing the viscosity of a formulation containing acetate and a therapeutic protein and formulations made using the claimed method. The present invention is also directed to a stable formulation produced by any of the methods of the present invention. The present invention is a also directed to an article of manufacture comprising a container containing a formulation of the present invention.La présente invention concerne un procédé de réduction de la viscosité d'une formulation contenant de l'acétate et une protéine thérapeutique, ainsi que des formulations obtenues à l'aide du procédé revendiqué.