PROBLEM TO BE SOLVED: To provide a pharmaceutical composition that effectively utilizes a culture medium of a stem cell such as an iPS cell.SOLUTION: The present invention provides a pharmaceutical composition containing a supernatant of a culture medium in which a stem cell is cultured while kept in an undifferentiated state. In the pharmaceutical composition, the stem cell may be a pluripotent stem cell.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】iPS細胞等の幹細胞の培地を有効活用した医薬品組成物を提供する。【解決手段】 幹細胞を未分化状態で維持培養した培地の上清を含む、医薬品組成物が提供される。医薬品組成物において、幹細胞が、多能性幹細胞であってもよい。【選択図】なし