Self-propelled operating machine for collecting pruning residues from the ground, including a support frame (2), pick up and collection means (4), cutting and chipping means (5), mechanical dragging and transportation means (6) for dragging and guiding the pruning residues picked up by the pick up and collection means (4) up to said cutting and chipping means (5), a collecting box (8) and conveyor means (7) for conveying the minced material to said box (8). The pick up and collection means (4), said mechanical dragging and transport means (6) and said cutting and chipping means (5) are mounted on board of a secondary frame (13) supported by said support frame (2) so as to keep the mutual positioning during the operation of said operating machine (1) and said secondary frame (13) is rotatable so as to be tilting, with respect to said support frame (2) around an axis of rotation passing by the axis of rotation (Y-Y) of a roller of a cutting and chipping mill of the cutting and chipping means (5).