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Methods of treatment employing prolonged continuous infusion of Belinostat
专利权人:
TopoTarget A/S
发明人:
Nissen, Nis,Sehested, Maxwell,Jensen, Peter Buhl
申请号:
AU2009220942
公开号:
AU2009220942A8
申请日:
2009.03.06
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates generally to the treatment of diseases and disorders that are mediated by histone deacetylase (HDAC), for example, cancer, with Belinostat (also known as (E)-N-hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamide; PXD101; and PX 105684), and more particularly, to improvement treatments of such diseases (for example, cancers, for example, leukemias), which employ prolonged continuous infusion (e.g., prolonged continuous intravenous infusion) of Belinostat
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