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SUSTAINED RELEASE PHARMACEUTICAL DOSAGE FORM CONTAINING PHENYLEPHRINE
专利权人:
MSD CONSUMER CARE; INC.
发明人:
PATTON, JOHN, W,KABIR, MOHAMMED,REO, JOSEPH, P
申请号:
NZ57317406
公开号:
NZ573174A
申请日:
2006.06.01
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a pharmaceutical composition in the form of a solid dosage for oral administration, the composition comprising a core comprising phenylephrine or a pharmaceutically acceptable salt thereof in a sustained release matrix comprising hydroxypropyl methylcellulose and further comprising one or more hydrophilic or hydrophobic polymers outside the core, wherein the phenylephrine or a pharmaceutically acceptable salt thereof comprises approximately 1 to 25 percent of the tablet weight, and the hydroxypropyl methylcellulose comprises approximately 10 to 50 percent of the tablet weight and wherein the hydrophobic polymer is crosslinked acrylic acid.
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