BEAUMONT TIM,BROWN ERIC J,HAZENBOS WOUTER L.W,KWAKKENBOS MARK JEROEN,MARIATHASAN SANJEEV,XIA YI,KAJIHARA KIMBERLY,MORISAKI JOHN HIROSHI
申请号：
NZ61692110
公开号：
NZ616921A
申请日:
2010.07.15
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed is an antibody or a functional part thereof that binds to a serine-aspartate (SD) repeat dependent epitope on a SD repeat (SDR) protein expressed by a Staphylococcus species, wherein the antibody or functional part thereof is coupled to a cytotoxic agent to form an antibody-drug conjugate. Also disclosed is the use of the disclosed antibody-drug conjugate in the preparation of a medicament and/or prophylactic agent for treating and/or preventing a Gram-positive bacterium-related disorder in an individual.
