A liquid cooled thermal control system and method for cooling an imaging system are provided. One imaging system is a computed tomography (CT) system having a detector that is positioned on a detector rail. The detector includes a plurality of detector components. At least some of the detector components are configured to detect x-rays. A liquid cooled thermal control system is provided having cooling channels in thermal communication with the detector rail. The cooling channels have a cooling fluid flowing therethrough to control a temperature of the detector components in response to one or more disturbances that changes a temperature of the x-ray detector. A control module is also provided in the liquid cooled thermal control system to adjust parameters of the liquid cooled thermal control system in response to the disturbances.
